Posts Tagged TiEcon
Posted by Darshana V. Nadkarni, Ph.D. in Big Data -Cloud -IoT-Software -Mobile -Entrepreneurship, Biotech - Medical Device - Life Science - Healthcare on March 23, 2020
The looming threat of Covid-19 and the grim reality of the toll that novel coronavirus takes on humankind, makes it imperative that we find a way to prevent the spread faster and with less cost. Currently nine out of ten drug therapies fail mostly between phase 1 trials and regulatory approval. The estimated cost of developing a new treatment is around staggering US $2.6 billion. While this article won’t address it, I want to mention that many bio/pharma companies are working with repurposed drugs to find a cure and at least 69 drugs have been identified as treatment possibilities. Drugs also have side effects and need to be tested for safety. Let us focus for a while on search for the vaccine.
Many companies including Moderna, CureVac and BioNTech are working on vaccines. With the help of Machine Learning, Artificial Intelligence and other technologies the hunt for new pharmaceuticals and appropriate chemicals is expected to be quicker, cheaper and more effective. Novel coronavirus presents the most unprecedented challenge to date because of the speed with which it spreads.
Who better than a supercomputer made by a company that has been on the cutting edge of innovation for over a century, to take on this speed challenge? IBM scientists instructed the world’s fastest computer to tackle this challenge at its Oak Ridge National Laboratory in Tennessee. Summit can run 200 quadrillion computations per second. The scientists ran thousands of simulations to analyse which drug compounds could stop the coronavirus from infecting the host cells.
Summit, an IBM supercomputer equipped with the “brain of AI” identified 77 compounds (from over 8000 compounds) that could be efficacious in preventing coronavirus from spreading in the host. This is promising news in humanity’s quest for an effective vaccine against the virus. These findings are published in the journal ChemRxiv and give us hope although road is still long to get there.
With increasing computer processing power and advanced algorithms, AI has been employed to analyze large data sets with greater efficiency and will likely lead to many exciting innovations. While AI and ML show promise to change every industry sector for the better, artificial intelligence, machine learning and deep learning have become the most widely discussed topics in the healthcare sector and the excitement keeps growing.
I will be looking forward to hearing about new innovations AI/ML at #TiEcon2020. Stay tuned for new dates for the conference at http://www.tiecon.org and on this blog.
Posted by Darshana V. Nadkarni, Ph.D. in Big Data -Cloud -IoT-Software -Mobile -Entrepreneurship on April 21, 2015
Oil and gas industry may have been in the headlines for occasional security glitches or even plant explosions. But what is often not mentioned, is a quite transformation happening inside the industry, to improve daily operations and safety. The technology adoption rate may be slower in this industry, due to sensitivity around safeguarding of trade secrets, IP issues, and data security concerns. But there is an increasing recognition of the need for enhanced operational excellence, in this industry, concerned with confining costs and refining margins.
The unconventional and controversial practice of horizontal drilling combined with hydraulic fracturing (converting organic matter within the rock to synthetic oil and gas), have been recent game changers. Apparently what can be produced by a vertical well in 30 to 35 years, can be done in a horizontal well, in a span of mere 6 months, environmental concerns notwithstanding.
There is now a thirst for innovative ideas within the industry, to minimize negative environmental impact, increase safety, contain costs, and enhance operational efficiency. Many oil and gas service centers have opened innovation centers in Silicon Valley to enhance implementation of new ideas. With the help of emerging technologies in visualization and complexity management, and with advances in cloud computing, big data analytics and Internet of Things, the industry is poised to transform itself for the better.
Neal Dikeman, Senior Venture Principal at Shell Technology Ventures, the corporate venture capital arm of Royal Dutch Shell, will give a keynote address at TiEcon, 2015. Join in discussions and learn how startups and large players are partnering to disrupt the current practices in Oil and Gas industry. Register at https://www.123signup.com/register?id=ygszb&ref=4182698 to get a $100 discount on the two-day conference at the non-member rate. When prompted, enter the promo code VOL500 at checkout:
Rakeysh Mehra, highly acclaimed Bollywood Filmmaker & Screenwriter, will speak at TiEcon 2014. Have you registered? You can register as my guest through the link http://tinyurl.com/kr2hkcw and enter code “TiEvalue” to get $100 off.
The process of filmmaking begins with a great story and then the filmmaker or the producer needs to work with the screenwriter to develop the story or screenplay they have just purchased. Rakeysh Mehra is an Indian filmmaker and screenwriter, known for writing and directing such films as Rang De Basanti (he won Best Director Filmfare Award for it in 2006) and directing blockbuster “Bhaag Milkha Bhaag”, starring Farhan Akhtar as Milkha Singh, India’s legendary runner (here’s link to my review http://bit.ly/1cUwG4o). “Bhaag Milkha Bhaag” acquired international fame and was nominated for 10 awards. Obtaining the right script and developing it into a good screenplay and then directing it into a successful film, is a highly challenging process, in the cut throat film world. One needs to understand and develop the characters, ensure the dialogues are not lame, understand the story structure, identify the genre or the blend of genres and Mehra is brilliant, with each of the steps of filmmaking.
Currently, India, the largest democracy in the world, is busy with the process of deciding its new leader. Voting is in full swing, in India. Mehra has been a critic of the vote bank politics and currently he is campaigning to introduce e-voting to facilitate voting by travelers. Mehra is also deeply committed to children and the education system in India. Regarding “Bhaag Milkha Baag”, Mehra said that to see the movie connect with children as young as six and eight, was the biggest part of his success with the movie that he is proud of. He has criticized marks-driven, education system in India saying that it emphasizes test scores over actual learning and achievement. Perhaps his next movie will address this issue? The filmmaker was location hunting recently in Jodhpur, for his upcoming film. Will there be announcements? Mehra will give keynote address on the morning of day 2 of the conference.
See discount codes to register for TiEcon 2014, www.tiecon.org and for Health Technology Forum
www.tiecon.org – If you are a professional in #healthIT, #digital health, #internetofthings, #cloud, #bigdata or related, then this is the conference, you don’t want to miss – It offers a fabulous opportunity to network with 3000+ professionals and listen to top notch speakers and panelists. Register for #TiEcon (May 16 & 17 at Santa ClaraConvention Center) as my guest, at link http://tinyurl.com/kr2hkcw & enter promo code tievalue to get $100 discount.
Healthtechnology Forum conference http://www.healthtechnologyforum.com, focused on exploring pathways to sustainable health, is on May 20 in SF. Please register for the conference as my friend, with the discount code “HTF14-FriendOfOrganizer” and send me your first & last name at wd_darshana at hotmail dot com, to get $150 off the price of the ticket. Also check out & participate in code-a-thon on patient engagement, for May 8. Over 20K+ in prizes.
JOBS: are posted at the link http://bit.ly/1o85CTM
Posted by Darshana V. Nadkarni, Ph.D. in Big Data -Cloud -IoT-Software -Mobile -Entrepreneurship, Biotech - Medical Device - Life Science - Healthcare on April 16, 2014
Life Science Industry gearing up for Innovation: Code-a-thon (Health Technology Forum), TiEcon, EPPIC event
Code-a-thons are fun and also highly productive live events that bring together developers, designers, innovators and entrepreneurs, brimming with new and exciting ideas on applications and tools for any given problem. Health Technology Forum in San Francisco was formed with a mission to improve healthcare through technology. In 2013, HTF organized a very successful code-a-thon that focused on serving the needs of the underserved populations. This year again, HTF has organized a code-a-thon to precede (by about a week to 10 days) its annual conference focused around the theme of Pathways to Sustainable Health, on May 20, at Parc 55, Wyndham Hotel, SF. Additionally, HTF has proposed a series of events to follow the weekend code-a-thon challenge, including a unique second phase to enable the winning team to be placed on-site at one or more safety-net hospitals.
So how do code-a-thons help spur innovation? These short and focused events often result in the rapid development of breakthrough concepts and working prototype applications. Code-a-thons highlight a problem in need of a solution. This spotlighting of the problem, with clarity around its challenges and opportunities, helps the problem to remain the primary focus of innovation, and not the technology. This is a good mental discipline for enthusiastic bright innovators who tend to fall in love with their own idea, and often fail to pay heed to the needs of the market. The ideas and technologies that come out of code-a-thons often lead to creation of actual products that can be deployed in the marketplace. Further, if these innovators would receive coaching from stakeholders within the hospital centers then it is inevitable that the positive impact will be enormous and immediate, in creating new innovative solutions, for sustainable healthcare. Few can argue that our healthcare system needs an overhaul, and something that will greatly impact the transformation in the healthcare system is the impact that Big Data will have. For instance, Big Data can help empower patients to be in charge of their own health. From providing access to their medical records, to enabling continuous health monitoring, it will help inform and empower patients to be proactive managers of their own health. Similarly, mounds of clinical and epidemiological data can lead to greater insights in diagnosis and therapeutics of various diseases. The requirements of this particular code-a-thon will be centered around developing and designing the prototype of an app that supports the collection and communication of health care data about key diseases and behaviors. Please stay tuned for more information, and sign up for the code-a-thon and for the annual conference at www.healthtechnologyforum.com and follow them on twitter @healthtechforum. You can follow me on twitter @DarshanaN.
Additionally, mark your calendar for 2 other interesting life science events.
May 16, 17 is #TiEcon 2014, the largest entrepreneurship conference, at Santa Clara Convention Center, CA. The Healthcare Track on Day 2 will feature panels on exciting topics like “Harnessing Healthcare Data”, “Engaging Patients of the Future”, “Where the VCs are Investing in Healthcare” and more. Register by May 1, for www.tiecon.org through the link http://tinyurl.com/kr2hkcw as my guest and enter promo code tievalue to get $100 off.
May, 6 EPPIC event – EPPIC frequently spotlights success stories of local entrepreneurs and on My 6 at Cubberley in Palo Alto, will host Dr. Sarvajna Dwivedi, Founder of Pearl Therapeutics which was acquired last year, by Astra Zeneca for $1.15 B. Register at www.eppicglobal.org.
http://www.bio2devicegroup.org is a group that meets every Tuesday, in Sunnyvale and hosts speakers on a wide range of healthcare topics. Pre-registration required for “Second Tuesday of the month meetings” and all other meetings are free and open for walk-ins. For information on any of these events, feel free to send me an email at wd_darshana at hotmail dot com.
Posted by Darshana V. Nadkarni, Ph.D. in Biotech - Medical Device - Life Science - Healthcare on April 14, 2014
Dr. Mark Borsody, Founder and Chief Medical Officer at Nervive Inc, spoke about stroke healthcare, at www.bio2devicegroup.org event.
Stroke has been a #1 cause of severe disability, #2 cause of death in the world (responsible for more than 5 million deaths, each year), and it is 4th leading cause of death in the US. About 800,000 people in the US have stroke, each year. One American dies from stroke, about every 4 minutes. In fact, stroke is responsible for putting the biggest healthcare burden, worldwide and the burden is likely to increase in the foreseeable future, said Dr. Borsody. Stroke results from “plumbing problem”, in the brain. Ischemic stroke is caused by blockage of a blood vessel due to reasons like thrombosis or arterial embolism. Hemorrhagic stroke is caused by bleeding of blood vessels of the brain, either directly into the brain or into the surrounding brain tissue.
While treatment options for hemorrhagic stroke are limited, current treatment options for ischemic stroke include intravenous “clot busting” through tissue plasminogen activator (tPA) or through endovascular catheter devices for blood clot retrieval. Worldwide, an estimated 180,000 tPA treatments are done every year and 22,000 clot retrieval treatments are done.
Honing in on the major problem, Dr. Borsody discussed why do so few patients with stroke receive timely treatment. Timely intervention is the key for treatment of stroke. Like all cells in the body, neurons and other brain cells require oxygen and glucose delivered through the blood in order to function and survive. A few minutes of oxygen deprivation can kill millions of neurons. Additionally, stroke can provoke inflammation, swelling (edema), and other processes that can continue the damage for hours or days after the initial attack. However, often treatment of stroke within 60 minutes is very rare due to the time required for patient transportation and in-hospital evaluation. Effective treatment for stroke can be simple, but it needs to be immediate. So how come there aren’t many innovations to bring the treatment to the patient, even to buy them some time?
Nervive’s Vital Flow Stimulator is a simple device that is aimed at targeting the facial nerve behind the middle ear. The objective is to control the cerebral arteries through the facial nerve, which regulates the function of the arteries. It is comprised of 3-4 cm coil placed over the ear. Magnetic fields readily penetrate any tissue and creates electrical currents in neural tissues, leading to axonal and soma depolarization. Early indications are that it is effective in treating ischemic stroke and it is safe in ischemic and hemorrhagic stroke. This device is moreover, simple enough to use without any special training. Vital Flow complements other therapies and bring exponential benefits of rapid treatments. The device will be inexpensive, portable, and extremely easy to transport in the ambulance. The treatment can be administered within a few minutes. Animal studies show increased blood flow after facial nerve stimulation and improvement in several measures after stroke.
Ending his talk, Dr. Borsody said, Nervive has a strong IP position, the technology is targeting a market with huge potential, and it is substantiated by preclinical and clinical science. They are starting fund raising for series A round. To emerge from the dark ages of stroke healthcare, we need some disruptive, out of box (out of hospital) thinking, said Dr Borsody.
Mark your calendars for following events……..
May, 6 – EPPIC will host Dr. Sarvajna Dwivedi, Founder, Pearl Therapeutics that was acquired by Astra Zeneca for $1.15B, last year. Register at http://www.eppicglobal.org, @EPPIC_GLOBAL
May 16, 17 – #TiEcon 2014 will feature Healthcare Track to showcase and discuss new innovative technologies in Life Science and healthcare industries, @TiEcon
May, 2014 – Healthcare Code-a-thon will be hosted by http://www.healthtechnologyforum.com @HealthTechForum
May 20, 2014 – “Pathways to Sustainable Health” conference hosted by http://www.healthtechnologyforum.com
You can follow me on Twitter at @DarshanaN
Every Tuesday exciting speaker – http://www.bio2devicegroup.org
Posted by Darshana V. Nadkarni, Ph.D. in Big Data -Cloud -IoT-Software -Mobile -Entrepreneurship on May 7, 2013
“Is it useful? If not, it better be entertaining. Else, it goes into the basket called useless”. With this simple mantra and simple philosophy for life, Manoj Bhargava, possibly the wealthiest Indian in America, leads 5-Hour Energy, the company that makes tiny bottles, packed with nutrients. Most of the company meetings last 30 seconds to a minute, says Bhargava, who leads the $1 billion+ company, with a lean, non hierarchical staff, of 60 people. “We are not efficient, we just don’t do useless stuff”, he says. Good advice! I can see how my efficiency would get a boost, if I stop doing useless stuff on my blog, twitter, facebook and take a big gulp of the 5-hour energy drink!
Bhargava’s approach to marketing and advertising is just as simple. With the belief that one may not be thirsty and need the energy jolt at the same time, tiny 2 oz. energy bottles packed with functional nutrients, B vitamins and amino acids, are strategically designed to be placed at the check-out counters and at easy point-of-sale locations; and are believed to have covered 90% of the energy shot market. Explaining one of their first ad that was nominated as one of the worst ads on TV, he says, “we don’t tell a joke and then name our product; our approach is to tell what it is”. This ad increased sales by 50% in 3 months.
Bhargava started plastics raw material company in 1990 that grew to $20 million in sales, before he sold it to a private equity firm. He then started a consumer products company, Living Essentials, out of which came 5-Hour Energy. His stake in Living Essentials is over $3 billion. Bhargava is as generous a philanthropist, as he is successful at entrepreneurship. He has contractually pledged a billion dollars to charities that fund medical research. Bhargava was awarded “2011 Newsmaker of the Year” award and was named Ernst & Young’s “Entrepreneur of the Year for 2012”.
TiEcon is around the corner. Register before the event is sold out at www.tiecon.org.