Posts Tagged healthcare

Life Sciences Industry Outlook for 2018: Post BiotechShowcase & JPM


Image result for Biotech Showcase 2018, JPM18JPM 2018 and concurrent events just ended with what may be one of its biggest draws.  As many as 10,000 people from life science industry and its related sectors are likely to have descended upon the city, during last four days.  In addition to JPM event itself, everything health was under review and up for discussion at various conferences including at EBD Group & Demy Colten’s #BiotechShowcase #DigitalMedicine #BTS18 and #WuXiGlobalForum2018 . Networking and deal making continued late in the nights at various receptions held across the city. Receptions by legal firms like #WilsonSonsini #MoFoLLP #ReedSmithLLP attracted some of the biggest crowds.

IMG_20180110_170128791.jpgOverall the tone for 2018, seemed highly optimistic.  BiotechShowcase held a media roundup and echoes of optimism were heard from almost all panelists @barbara_ryan12 @TriangleInsight @CarolineYLChen @adamfeuerstein @statnews @SFBIZronleuty @BrittanyMeiling @endpts @juliet_preston @medcitynews @ldtimmerman .

Image result for biotech innovationThere is a general agreement that the pace of #innovation in biotech greatly accelerated in 2017 and is likely to continue. According to Luke Timmeerman, “sheer velocity of news in healthtech innovation is fascinating”. Transformative therapies across huge and diverse range of diseases are increasingly focusing on cures and going beyond the short term treatment focus. The surge of innovation has been led by focus on oncology although concern was also raised in one of the panels that we still continue to get stymied and realize how friggin smart the disease of cancer is and if we will truly crack the code on cancer in the immediate upcoming years. All signs are however, that next year we may see critical data from some clinical trials in immuno-oncology space that can cause market spikes.

Here are some areas of concern raised in some of the panels. In 2017, a slight dip was observed in the areas of orphan and rare diseases. Also there seemed to be a general consensus that we need smart policies that incentivize new anti microbial drugs and other treatments for infectious diseases. Due to increasing resistance of antibiotics, there is an ongoing and real fear for some of the infectious diseases to turn into pandemics. These are areas that bold entrepreneurs may focus on. Also medical devices continues to remain somewhat underfunded. Discussions around accelerating healthcare costs and drug pricing issues creeped over into many panels. Entrepreneurs with disruptive pricing innovation in product development as well as healthcare can easily have a tremendous leverage. It can’t be overstressed that finding effective pricing solutions holds key to continued and sustainable growth in healthcare sector.

Discussion in one of the panels focused for a few minutes around large investments in life sciences and if that indicated a healthtech bubble that may be due for a crash.  Indeed, some experts observed that pace of 2017 is unlikely to continue and there may well be a slight dip in 2018. But overall the consensus seemed to be, that a steep and deep pipeline of innovation in R&D is likely to prevent a crash, and the venture funding blizzard is likely to continue. Overall, the feeling among investors and healthcare experts was that among the industry, there is a strong focus on science and people are pursuing innovation with discipline that will ensure unprecedented mechanisms and novel medicines. All this activity is taking healthcare to a new level of cures and sustainability and stability from temporary treatment focus. Exciting indeed to be living in this era of amazing healthcare innovation.

 

 

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Biotech Showcase 2018 Preview: What it will mean to be living in the era of cures & more VC money


Lunch plenary sessions are always a huge draw at Biotech Showcase and are very exciting. On day one, a panel moderated by Sara Radcliff from CLSA will take a 60,000 feet view and will discuss what the future holds for biotechnology and life science sector. Biotechnology is increasingly going beyond treatment to focusing on cures. Day 2 panel moderated by Alice Valder Curran from Hogan Lovells with Eric Aguiar from Aisling, Philippe Lopes-Fernandes from Merck and Camille Samuels from Venrock will discuss “what it means to be in the era of cures”. The panel will discuss how public and private markets are still catching up with new policies on coverage, pricing, and liability issues, making it even more challenging to decide what product candidates to pursue.  Lunch panel on day 3 moderated by Ellen Corenswet from Covington & Burling LLP and populated by prominent VCs and industry experts will reflect on 2017 surge of venture capital.
Image result for future of healthcareImage result for healthcare venture capital

Besides all day information packed sessions focused on key diseases that are getting attention http://bit.ly/2pA45B7 , there are interesting panels and sessions on treatment modalities that are the garnering attention of investors and entrepreneurs http://bit.ly/2CjET4G .  And then there will be panels discussing investment in healthcare, what to expect in 2018 from investment perspective and what are likely to be new drivers of innovation in drug development, and new targets, new trends and new combinations in treatment.

Besides three action packed days, the evenings will be packed with countless receptions and networking will continue late into the night. Concurrent 36th annual J P Morgan Healthcare Conference is expecting 400+ public and private companies to deliver presentations to over 8000 attendees. San Francisco will be taken over by everything health for three days, from January 8th through 10th, 2018.  

While JPM conference is by invitation only event, registration is open for Biotech Showcase at conferences@ebdgroup.com or at https://ebdgroup.knect365.com/biotech-showcase/agenda/1

 

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Biotech Showcase 2018 Preview: Treatment focus on microbiome, regenerative medicine, gene & immuno therapies


Image result for biotech showcase 2018Biotech Showcase taking place concurrently with the J P Morgan event in San Francisco, will host more than 3,500 attendees and 900+ investors. This event considered to be a critical strategic benchmark for business development activities in biotech, medtech, pharma and digital health, is regarded as among the year’s most important investor meeting place and sets the tone for financial health in these sectors, for the coming year.  Speakers and attendees at Biotech Showcase, will participate, network and listen to over 400 company presentations. Over 2,100 companies from 50+ countries will participate.  Besides 7000+ one on one meetings, general sessions will focus on a number of topics that are significantly expected to impact the healthcare arena. Here are some of the treatment modalities that are getting interest from both investors and entrepreneurs.

A panel moderated by Joseph Gulfo, Executive Director at Lewis Center for healthcare innovation and technology with Thomas Hallam, CEO of Leading Biosciences, Arpita Maiti, Senior Director, ES&I at Pfizer, Glenn Nedwin, CEO of Second Genome, will start day one. Microbiome refers to internal ecosystem of bacteria, widely believed to be residing in the gut. By some researchers estimates, over 90% of all diseases can be traced to the gut and health of the microbiome. However, new research on lung, skin, inflammation, immunology, and neuro microbiome is bringing together experts in neuroscience, gastroenterology, microbiology and more to unlock even larger role that microbiota plays in interacting with itself and its human host, in understanding disease and health and better understand possible treatment modalities.Image result for microbiome, neuro

Image result for regenerative medicineA panel moderated by Janet Lambert, CEO at Alliance for Regenerative Medicine will discuss next gen cell based immunotherapies with panelists Robert Preti from Hitachi, Bob Azelby from Juno Therapeutics, Manuel Litchman from Mustang Bio, James Noble from Adaptimmunie, Pascal Touchon from Novartis and Scott Walchko from Fate Therapeutics.  Immunotherapies use body’s immune system’s natural capacity to detect and destroy abnormal cells. Immmunotherapies have generated great deal of interest, specifically for treatment of cancers because these regimens present fewer side effects and have less potential for creating resistance when treating microbial diseases.

Image result for gene therapyGene therapies using genes to treat or prevent diseases, indicate promising though yet risky treatment options. What does the future hold for gene therapies, specially beyond rare diseases?  Bill Lundberg from CRISPR and Geoff Nichol from Biomarin will discuss outlook for gene therapies.  

PS: Here is link to my earlier blog on disease areas that will generate interest and renewed attention in some of the panels http://bit.ly/2pA45B7 . Registration is open for Biotech Showcase at conferences@ebdgroup.com or at https://ebdgroup.knect365.com/biotech-showcase/agenda/1

 

 

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Biotech Showcase 2018 Preview: Disease focus: infectious diseases, metabolic syndrome, skin & more


Biotech Showcase taking place concurrently with the J P Morgan event in San Francisco in January 2018, is an investor and networking conference.  Many partnerships and collaborations will be forged with over over 7000 one on one meetings, with opportunities for eager innovators to seek out enthusiastic investors.  Besides one on one meetings, general sessions will focus on a number of disease areas that are significantly expected to impact the healthcare arena.  More blogs to follow and will highlight focus on new treatment modalities.

Image result for skin diseases highlight internal problemsA panel led by Jennifer Goldstein from Silicon Valley Bank will focus on body’s largest organ that is often misunderstood and frequently underrated, the skin. Panelists Alan Dunton from Purdue Pharma, David Giljohann from Exicure, Jennifer Good from Trevi Therapeutics, Shelley Harman from Aegle and Mark Wilson from MatriSys will discuss early signs and symptoms on the skin that often signal infectious and internal diseases.

Image result for antibiotic resistance, infectious diseaseAntimicrobial resistance or (AMR) is increasingly a prominent public health concern and has been highlighted by both WHO and CDC. Since the discovery of first antibiotic penicillin in 1928, more than 100 compounds have been created but no new class has been found. In panel moderated by Bibhash Mukhopadhyay at New Enterprise Associates, leading anti-microbial drug development experts, Alan Carr of Needham, Julia Gregory from Contrafect, Kenneth Hillan from Achaogen, Gregory Mario from Taxis Pharma, John Rex from F2G, and Chris Stevens from Arsanis will discuss the tailwinds and headwinds in this space that is getting a fresh second look from both experts and investors.

Image result for metabolic syndromeCurrent epidemic of metabolic syndrome will be the focus in a panel moderated by Philip Kenner from ClearView with panelists Deborah Dunsire from DTuit, Tomas Landh from Novo Nordisk, Harith Rajagopalan from Fractyl Labs, and Wendye Robbins from Blade Therapeutics. Having any one of the risk factors like high blood pressure, high blood sugar, obesity, high cholesterol, or high triglycerides can greatly increase health risk.  However having a cluster of these conditions together indicate metabolic syndrome and vastly increase health risk. Metabolic syndrome is on the rise, reaching epidemic proportions according to some health experts.

While JPM conference is by invitation only event, registration is open for Biotech Showcase at conferences@ebdgroup.com or at https://ebdgroup.knect365.com/biotech-showcase/agenda/1

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Tale of two Americas influencing #Election2016 & Open Letter to Hillary Campaign


Here’s something to think about… the country is soooo divided that Americans are living two distinctively different realities; it is almost like they are living in two different nations.

America 1

Imagine that you live in the Appalachian mountains off of Virginia or Ohio.  Jobs in mining and manufacturing that were once plentiful are gone and no one has offered you re-training to operate in a different reality that has been emerging.  Opioids & alcohol are easily available to dull your pain (in fact, in parts of Ohio, first time more people are dying from opioid addiction than natural causes).  You see yourself as having no future; the best is behind you. You are enormously proud of your heritage, hard work ethic, and your religious values.

Church used to be your anchor but now church attendance has fallen; you have no anchor. You just want someone new at helm in this country, to shake things up – you don’t care how or who it is as long as the person talks to you in a language you understand and holds someone; an outsider responsible for your plight. Your current reality is so painful that you believe you once lived in a phenomenal nation, and you are losing it to outsiders who steal your jobs. Perhaps you don’t see many immigrants where you live, but you hear statistics of jobs being offshored, terrorists rarely target your geographical areas and you don’t often see women in hijabs but you hear about terror attacks when they happen and it scares the s*&^ out of you. Lowering or raising federal minimum wage has no impact here because there is no economy, no jobs. If someone tells you they will build a wall to keep immigrants out then it resonates with you.  If someone promises to bring back outdated mining jobs back, you are filled with hope.

America 2

Now imagine  you are living in a place like Silicon Valley in California, a place on the cutting edge of innovation.  There is a different social and economic reality.  You work with Muslim engineer, Chinese American scientist, Mexican American patent attorney, Iranian American realtor and your child’s teacher is lesbian.  These people are not aliens but your next door neighbors and share similar interests and values, as you.  Price for 2 BR condo in newly built (and fraught with problems), millennium towers in San Francisco costs around $2M and when economy tanked in 2009 (right after George Bush left office), California was hit harder than Ohio and Indiana.  The number of people filing for bankruptcy protection in the first quarter of 2010 ranked California at number one for bankruptcy protection. Right after Florida and Nevada, California also had one of the highest foreclosure rates with 1 in every 192 houses being foreclosed.

I can personally vouch to the impact of extremely high unemployment, while living in a state where everything is more expensive.  Both my businesses died.  I offered recruitment and soft skills training, but no one was hiring and no one had budget for soft skills training.  In 2009, I made less than $10,000.  I sold my house and while my business continued to remain in a nearly dead mode, in 2010 and 2011, I pounded the pavement for hourly jobs at Starbucks etc. for which I was always considered overqualified.  But California is back in business and so am I; better than ever before.

How did California do it?  I think California did it by leveraging the global trends and with a unique blend of cutthroat captialistic competition and compassionate socialism.  Corporations may not be people but both companies and people in CA exhibit this blend of competition and compassion.  I have some more thoughts on this and if I am not distracted by other things, I may study this more and write another blog.  But for this post, I want to focus on what is required of a political leader to bring the two Americas together. 

Open letter to Clinton Campaign

Henceforth, Ms. Clinton must maintain a laser sharp focus on issues that matter in the swing states.  All focus should be solely on large percentage of undecided voters who swing back and forth between Trump and Hillary.  Stop talking about how racist Trump is or that he is adhering to Alt-Right.   More people learn how racist he is, more votes it is getting him. Trump’s entire candidacy is based on inciting hate and division and taking his message to the masses is only enabling him.  Besides, he has so much air time, everything he does and says is covered.

While American women would largely care for issues like equal pay for equal work, do not focus on sexism in Trump campaign.  In California, I saw ads targeting women, with mention of Trump’s abominable remarks denigrating women.  But California is tuned in already,  In the swing states, there are likely to be more women in committed relationships and more than right to choose and equal pay, they care more for jobs for their husbands.  Still for many, it is a man’s serious and primary responsibility to earn a living.

Do not mention immigration.  Trump has made entire immigration dialog in the country about sound bites (big wall, beautiful wall, Mexico will pay for it, deporting etc.) and more confident and more racist his sound bites, more they are striking a chord.  He effectively created an environment of fear where soundbite solutions are very appealing.  I don’t believe Ms. Clinton can give any effective soundbites on immigration.  That is simply not her style and people are not in the mood to listen to logic on this issue.

Do not mention environmental issues.  While this has been President Obama’s crowning achievement, it does not figure in top 10 priorities when you put it on Maslow’s hierarchy of needs.  Americans are generally more present oriented but are certainly focusing squarely on short term and immediate benefits during this election season.  The more Trump talks about how things will change on November 8, less concerned people are about benefits to future generations.  

Also, do not focus in the debate on Trump’s lack of foreign policy experience.  Americans often care little about foreign relations.  President GHW Bush made great strides in foreign relations and he got little credit for it.  Besides Trump scored a victory looking Presidential in Mexico.  More than that, no one cares.

Image result for maslow's hierarchy of needsThink of Maslow’s hierarchy of needs that goes from fulfillment of basic needs and only after they are satisfied, it progresses to focus on social needs.  When people’s basic needs of healthy food, clean water, and safety are not satisfied, focusing on social issues like women’s rights, race relations, immigration, pay equality, and equal rights for LGBTQ, are a luxury they can’t afford.  While Trump may be trigger happy to get access to the nuke button, for America 1, it does not feel like a looming disaster; instead, it enhances their feeling of safety.

Here are the issues that Clinton campaign should singularly focus on.  

Focus on JOBS

Image result for jobsForget all incredible and horrific things said and done by Trump that make him unfit to be the President. Stay singularly focused on jobs and the economy and his lack of concrete plan to create jobs.  In his post convention interview with George Stephanopoulos, Trump was questioned about jobs.  See clip below at 11 minutes, where Trump when asked why he brings in people from overseas to work at Mara Lago resort in Florida, he tried to duck the question by taking talking about other companies offshoring jobs and Stephanopoulos keeps bringing the discussion back to his issuing almost 500 offshore visas since 2010 and Trump deflects it again saying everyone does it because they can’t find American workers.  Hummm, they can’t be re-trained for low level jobs then how is he going to pressure Samsung and Apple to bring skilled jobs outsourced to Indian and Chinese engineers at fraction of the cost, back to America?  Use this clip with Clinton’s concrete plan to continue to create job growth in America.  This is not a sensational piece of news that elite media (largely favored by America 2) will play over and over but you must capitalize on.

http://abcnews.go.com/ThisWeek/video/donald-trump-41028199

Respect & concrete benefits to America’s Veterans

Image result for war veteransAmerica owes to our veterans.  But that sincerity must be expressed with something more tangible than “America loves you and is deeply grateful to you for your service”.  If one vet feels strongly enough to give away his purple heart to Trump then that is one too many vets disillusioned, and whom we must re-engage with.  Our vets must have certain level of job security, access to constant retraining, access to healthcare, including easy access to mental healthcare.  There must be early intervention before PTSD takes an enormous toll on their lives and the lives of their loved ones.  Talk about how Obamacare has enabled easier access to healthcare for so many people.

Access to mental healthcare and PTSD treatment

Image result for PTSDTrauma has become a significant part of modern life.  It is not only our vets who need access to treatment for PTSD, but also foster care children who are often shuttled around from family to family, from one location to another.  Children who witness domestic violence, often suffer from PTSD, while their needs may be completely ignored at home and outside.

Concrete plan to deal with opioids and other drugs

 Image result for opioid addictionAs mentioned above, in parts of Ohio, first time more people are dying from opioid addiction than natural causes.  Obama administration and FDA has been deeply concerned about escalating use of opioids and other drugs but how frequently do we hear from Hillary campaign about the plan that is in process?  For instance, the Obama administration is making it easier for doctors and law enforcement to use anti-addiction drugs.  FDA is putting in place steps so that companies seeking approval of any new opioids, must include abuse-deterrent properties and appropriate labeling. But more importantly, there are concrete steps in place to deal with current trends of opioid abuse, including additional training to prescribers on pain management and safe prescribing, encouragement for abuse deterrent formulations, make naloxone more easily available to treat opioid overdose, and encouraging new class of pain medicines without the same risks as opioids.  Ms. Clinton must relentlessly address opioid abuse and significant strides being made under Obama administration to counter that.  

Finally, I humbly suggest that Hillary campaign and the media stop playing over and over and over Trump soundbites that show his racial, gender and other biases – contrary to people being turned off by such bigotry, in the climate of fear he has created and the foundation of hate he has laid, his bigotry gives people a feeling of safety and hope. Considered dialog detailing the history of events and people as done by Rachel Maddow and others and late night shows (Colbert, Noah, Bee, Oliver and others) that point out ridiculous aspects of Trump messages with humor, are however excellent.

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Disruptive Innovation on Boundaries of Disciplines – TiEcon tracks & Discount Code


Are you still playing inside the boundaries of disciplines?  Play on the boundaries, instead.  There are huge opportunities for entrepreneurship and innovation on the boundaries of disciplines.  All industries are impacted and transformed by the increasing interconnectedness with technological advances in IoT, Big Data, Cloud Computing, Machine Learning and more.  This transformation is most apparent in  heavily regulated and somewhat slower to change industries like, “Oil and Gas” and “Healthcare”.  Any industry that worked in a silo before is likely to leap forward into the new age.   These areas are likely to experience most disruptive innovation and are  brimming with opportunities for entrepreneurs thinking outside the discipline boundaries.

Oil & Gas industry is on the verge of major transformation.  Entrepreneurs with industry specific innovations to enhance operational efficiency and minimize negative environmental impact, will score big.  Most recent environmental concerns have been around the impact of fracking or hydraulic fracturing, a process by which water and sand mixture is pumped deep below the earth’s surface, into earth’s dense shale rock formations.  Fracking produces many long narrow fractures in the rock formation and helps convert organic matter embedded within the rock to synthetic oil and gas.  It has vastly improved oil production.  It is estimated that what can be produced by a vertical well in 30 to 35 years, can be done in a horizontal well, in as short a span as 6 months.  However, recent studies indicate that fracking has led to an increase in seismic activity.  Thus far the activity was minimal but it has now been growing in both strength and number, with increase in fracking.  Many Oil and Gas companies have established innovation centers in Silicon Valley to assess and garner technological help to expedite learning about environmental impact and explore if technology might help intervene to minimize negative impact, in addition to enhancing operational efficiency. 

Healhcare has also emerged as the most attractive area, pulling in major investment dollars.  Internet of things, for instance, will help bring in focus, the prospect of connected health.  As increasingly incentives are tied to preventative medicine, providers will look for opportunities for seamless, integrated care.   Cloud and big data will enhance the possibility to learn from collective knowledge, access wisdom of the crowd, and enhance quality of health with lesser investment of resources.  Big pharmaceutical companies and biotech will look to utilizing technology in bringing therapies to market, with minimal wastage of resources and dollars.  Opportunities exist to transform the process of drug development http://bit.ly/1xzpdFx& http://bit.ly/14pkhRO , to digital health advances enabling early identification and treatment of diseases http://bit.ly/11MlM9e , to even better monitoring of medical adherence.  While reimbursement is increasingly emerging as a major challenge, insurance providers will look for disruptive, and long term, cost saving innovations.

TiEcon 2015, largest entrepreneurship conference, taking place at Santa Clara Convention Center on May 15 and 16, will feature these new tracks on healthcare http://bit.ly/1OOCV9Z and oil and gas http://bit.ly/1HqQkoc, in addition to featuring companies and speakers making waves in Data Economy, Internet of Things, and Cloud Security tracks.

Register for TiEcon and come and play on the boundaries of disciplines; jump from track to track, network with multi-track participants, angels, VCs, and learn and get inspired.  TiEcon will take place at Santa Clara Convention Center, Santa Clara, CA on May 15 and 16.  Register through this link  https://www.123signup.com/register?id=ygszb&ref=4182698 to get a $100 discount on the two-day conference at the non-member rate.  When prompted, enter the promo code VOL500 at checkout.

PS –  I am looking to fill a number of full time and contract engineering opportunities in mechanical, quality, software, electrical, firmware engineering in CA & TX.  Details are posted in JOBS category at www.darshanavnadkarni.wordpress.com .   Some of my full time opportunities are very exciting with a huge potential upside and truly disruptive technology.  Resumes can be sent to wd_darshana at hotmail dot com

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Healthcare Track Preview at TiEcon 2015


Healthcare industry is poised to go through impressive transformation, in the coming decade.  What some experts have dubbed a 3D transformation, changes in life sciences are happening through massive changes in Diagnostics, Digital Devices, and Data.

English: USNS COMFORT (Feb. 15, 2010) Maj. Tom...

(Photo credit: Wikipedia)

Consider this.  TiEcon, the largest entrepreneurship conference, focused for several years on computing, storage, hardware, software, firmware, semi conductors, gaming and mobile technologies.  HealthTech was not the focus at TiEcon.  But HeathTech has recently emerged as one of the hottest areas to invest. Besides offering a special healthcare focused track, on day 2, May 16th, healthtech is integrally woven in most of the other tracks, at TiEcon 2015.  Technology has impacted all areas of our lives such that no entrepreneur could look at any industry as a silo.  To register go to https://www.123signup.com/register?id=ygszb&ref=4182698 to get a $100 discount on the two-day conference at the non-member rate.  When prompted, enter the promo code VOL500 at checkout:

In fact, most of the disruptive innovation is happening on the boundaries of disciplines.  This is most pertinent in life science, hospitals and healthcare, healthtech, biotech, pharma, drug development, medtech, digital health, mobile health, wearables space.  Every new intersection point between health and an emerging technology, brings its own terminology.  Collectively, the aim is to positively transform the quality of lives of healthy and sick people.  So how is life science focus woven across several tracks at TiEcon?

John Kapoor, a serial entrepreneur, who is number 577 on Forbes Billionaire List, is going to give a grand keynote address on day 2, Saturday.  Kapoor, whose net worth is estimated at $3.5B, has founded and guided two pharmaceutical companies, Insys Therapeutics and Akorn Pharmaceuticals and led them to exceptional success.  Pharmaceutical industry is slowly but surely changing to innovate faster, cheaper, more cost efficient process of drug development.  Here is link to my recent blog on novel approaches to drug development http://bit.ly/1xzpdFx .

English: South façade of the White House, the ...

(Photo credit: Wikipedia)

Here is another interesting keynote to watch out for.  After helping coin the term, “Data Scientist”, while still in the academia, D. J. Patil did some initial work on deciphering the complexity of the weather patterns and impact of bioweapons proliferation in Central Asia.  Here is link to my blog on Patil in 2013 http://bit.ly/YYyOxd .  After stints in eBay, PayPal and LinkedIn, Patil was appointed by President Obama, as Chief Data Scientist at the White House. Among other responsibilities, Patil will work on the Administration’s Precision Medicine Initiative, focusing on utilizing advances in data to enable clinicians select most effective treatments.  Here IBM’s Watson, an artificial intelligence system with access to millions and millions of pages of structured and unstructured data, to help in efficient diagnosis and suggest possible avenues for treatment, deserves special mention.  Here is my link to Dave Farucci’s keynote at TiEcon, several years ago http://bit.ly/JOZmwH .

Besides the keynotes and healthcare representation on panels in other tracks, Day 2 focused Healthcare track panels will address such varied topics as role of “Medical Devices in a Changing Landscape” and “Trials and Tribulations of Adopting Technology in Hospitals”.  Eminent speakers include, MD and CEO at Good Samaritan Hospital, Paul Beaupre;  Anupam Pathak, Founder & CEO of Lift Labs, acquired by Google X, Brett Knappe, Senior Director of Strategy at Medtronic; Satnam Alag, VP, Software, Illumina; and Darius Naigamwalla, President at Campbell Alliance.  Representation from technology rich companies such as IBM, GE, Google X, and Tibco, in discussions on healthcare, along with medtech and big pharma companies like Medtronic, J&J, 23&me, Illumina and Genentech AND representation from healthcare providers like Good Sam, will make for very rich dialogue.  Register for TiEcon at https://www.123signup.com/register?id=ygszb&ref=4182698 to get a $100 discount on the two-day conference at the non-member rate.  When prompted, enter the promo code VOL500 at checkout:

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Tackling Global Health – (Kim Bush, Gates Foundation) Keynote Preview at EPPICon 2015


With Obamacare, the discussion about national health has moved to front and center stage.  But what about the status of global health; what are the opportunities and challenges?   Just about a decade ago, availability of resources was the biggest problem in the arena of global health.  But with the rise in public and private giving, to a large part due to unprecedented giving by Warren Buffet and Bill and Melinda Gates, the challenge has now shifted to better coordination of resources for “equitable, inclusive & sustainable solutions”.  According to Council on Foreign Affairs, “for the first time in history, the world is poised to spend enormous resources to conquer the diseases of the poor”.

Logo da fundação Bill & Melinda Gates

Logo da fundação Bill & Melinda Gates (Photo credit: Wikipedia)

 

Kim C. Bush, director of Life Sciences Partnerships at Gates Foundation, is leading the efforts to broaden and deepen the foundation’s engagement and partnership initiatives with various healthcare industry sectors.  With an objective to address the critical global health challenges with speed and effectiveness, the foundation is bringing in the industry in this dialog, in a systemic manner.  The goal of the Gates foundation is to match global health priorities with the industry capabilities.  

Kim Bush will be giving a keynote address at 2015 EPPIC Annual Conference, on March 28th at Santa Clara Convention Center.   Entrepreneurs in life science arena, committed to solving some of the major health challenges of our times, may get big insights into where the gaps and the glaring problems are, as well as where the resources are being channeled.

Lineup of speakers on all panels at EPPIcon 2015, is very exciting, with plenty of networking opportunities thrown in.  Here is a link to the preview of one of the panels on Digital Health – http://bit.ly/1EQtd5y .  No doubt, connected, digital health will also play a prime role in advancing global health.  Come and participate in the dialog, network with like minded professionals in Silicon Valley, and hear from key opinion leaders, angel and VC investors and other industry leaders.  Early bird registration will expire at midnight today, March, 16.  Register today at www.eppicglobal.org .

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Also a plug for http://www.healthtechnologyforum.com 2015 annual conference on May 27 and 28 in Burlingame, CA. Early bird pricing will be effective till March, 31.  Panels include Innovations for the Underserved, Resilient Communities, Population Health Management, and the conference has a dedicated focus on making a positive difference and transforming health globally.  Register soon for an opportunity to hear great speakers and network with professionals committed to making a difference.

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Digital Health Panel Preview – EPPICon 2015


EPPIC annual conference is on March, 28 and early bird pricing will end on Monday, March 16.  Here is a sneak peek at one of the panels.  

Technology is impacting health in interesting ways and many exciting innovations in digital health are expected to change how diseases are tracked, reduce inefficiency in healthcare delivery, reduce costs, improve access to healthcare, increase quality, save resources, and make medicine more personalized.  Digital health panel at EPPICon 2015 has diverse and interesting lineup of speakers.

wpid-20150304_162558.jpgDr. David Persing, EVP, CMO, and CTO at Cepheid, had made an early resolve to have a positive impact on the world.  Guided by intellectual curiosity, while doing his pre-med, he discovered “the power of diagnostics”.  The company’s mission at Cepheid is to use the power of molecular diagnostics such that it would enable medical providers to identify and treat diseases early, increasing opportunities to improve patients’ survival and quality of life. Their cloud based platform, “The Digital Miasma” for monitoring of emerging infections earlier, is just launched and is in the implementation phase.

wpid-20150304_163547.jpgPanelist Deborah Profit is Director of Corporate Projects – Global Clinical & Business Operations for Otsuka Pharmaceutical Development and Commercialization.   OPC, is headquartered in Tokyo and is known for popular sports drink Pocari Sweat and energy drink Oronamin C.  OPC also developed Abilify, an approved drug treatment for certain mental illnesses, and as of 2013, annual sales of Abilify were over $8 billion a year, making it the highest grossing drug worldwide.  You would wonder what has that to do with digital health, until you consider the fact that patient non-compliance is one of the biggest challenges in many illnesses but specifically in mental illnesses.  Otsuka has recently made a deal with Proteus Digital Health for tracking medical adherence.  Proteus system includes sensor-enabled pills that embed intelligence into the pills so that their ingestion can be precisely tracked.  Personally, I am totally against drugs for mental illnesses, many of which do not work as expected; placebo effects are not well identified, clinical studies are often sponsored by drug companies and the list of side effects is daunting and being a psychologist, having seen side effects and heard them being discussed by my colleagues, I have developed absolute disgust for drugs for mental disorders.

Proteus “ingestible sensor” technology however, holds enormous promise for various indications, specifically for treatment and management of chronic conditions.  Otsuka plans to make use of Proteus Digital Health’s feedback system in its clinical R&D, presumably for its oncology products.

The next panelist, Dr. Marsha Rose Gillentine is Director of Biotechnology/ Chemical Group at Sterne Kessler Goldstein Fox, LLP and has intimate knowledge and understanding of patent litigation strategy in small molecules, ploymorphs, chemical synthesis, pharmaceutical formulations, methods of treatment, drug delivery devices, animal models, vaccines, polymers and more.  Her experience encompasses working with clients to implement lifecycle management strategies, specifically at it relates to personalized medicine patent portfolios.

Members of the Paris Medical Faculty (1904) An...

Members of the Paris Medical Faculty (1904) André Chantemesse (1851–1919) Georges Pouchet (1833–1894) Paul Poirier (1853–1907) Georges Dieulafoy (1839–1911) Georges Maurice Debove (1845–1920) Paul Brouardel (1837–1906) Samuel Pozzi (1846–1918) Paul Jules Tillaux (1834–1904) Georges Hayem (1841–1933) Victor Cornil (1837–1908) Paul Berger (1845–1908) Jean Casimir Félix Guyon (1831–1920) Pierre-Emile Launois (1856–1914) Adolphe Pinard (1844–1934) Pierre-Constant Budin (1846–1907) (Photo credit: Wikipedia)

Jared Heyman is founder and CEO of CrowdMed, a brilliant innovative site that takes connected health to a whole new plane.  Often individuals afflicted with rare or neglected diseases, go from doctor to doctor, from pillar to post, just to accurate diagnosis and then they face whole set of new challenges for treatment.  CrowdMed is seeking to solve most challenging medical cases, worldwide, with speed and accuracy online, by harnessing the collective wisdom of the crowd.

The Digital Health Panel at EPPICon 2015, will be an exciting panel.  Agenda for the entire day looks very interesting and there will be plenty of opportunities for attendees to network and mingle with like-minded professionals.  The conference is on Saturday, March 28th at Santa Clara Convention Center, in Santa Clara, CA.  Early bird pricing has been extended till March, 16.  Please register for the event at the link http://tinyurl.com/o4cj3ow or from www.eppicglobal.org .

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Life Science and Investment Partnership Opportunities with China – 2015 OneMed Forum & OneMed China Forum


Opportunities and challenges for life science companies, in working with China, was a big focus of OneMed Forum, 2015.  OneMed Forum 2015, took place at the same time JP Morgan event was happening in San Francisco.

USS San Francisco (CA-38) entering San Francis...

USS San Francisco (CA-38) entering San Francisco Bay under the Golden Gate Bridge, December 1942. The structure on the lower left is Fort Point. This picture was taken December 11, 1942, as the USS San Francisco, severely damaged in the Naval Battle of Guadalcanal the previous month, returns to her namesake city. The ship was en route to the Mare Island Navy Yard for repairs. (Photo credit: Wikipedia)

The OneMed Forum conference with a mission to bring healthcare companies and investors together, opened on January 12, 2015 with a panel that discussed Opportunities in China.  China has seen a very rapid economic growth that has spurred tremendous interest in investing in promising products and technologies, particularly in the healthcare arena.  This panel explored strategies to access the Chinese market.  There was a lot of stress on getting local partners early on.  The panel also discussed deal structure alternatives for companies looking to secure capital, as well as licensing and distribution opportunities in China.  (PS – please see link  http://bit.ly/Zcwxqi  for Life Science job opportunities in China)

After OneMed Conference ended on January, 13th, OneMedChina conference occurred at the same venue.  After the opening remarks by Tony Chu, Founder and Partner with The Pharma Partners, a panel discussed a topic of great general interest “Investing in America”.  It is no more that American companies are chasing Chinese investors, but also many Chinese investors are actively seeking investment opportunities in North America and Europe, particularly in the healthcare arena.  There is a great deal of interest among Chinese investors in technologies that would address Chinese and global markets.  The panel of experts included, Mr. Kevin Chen, Partner and Head of Healthcare Investment, Sequoia Capital China, Mr. Xiangyu Ouyang, Partner & Head of Healthcare Investment, Legend Capital, Dr. David Wang, Partner, OrbiMed China and Mr. Edward Zhou, Partner and Head of Healthcare Investment, New Horizon Capital.  The panel shared insights on investment strategy to follow and shared their current global investment focus.

Next panel on “How to build a successful partnership with a Chinese company” was represented by Dr. Sanuj Ravindran, Global Head of Business Ventures, The Medicine Company and Mr. Andrew Wong, VP of Business Development at SciClone Corporation.  Both panelists stressed the need for local partners.  Wong said that hiring a local advisor will help bridge the culture gap.  Ravindran stressed the need to get on the ground and spend some time to get business and cultural understanding for such partnership to get off to a good start.

These panels were followed by lunch with extended networking time.  Rooms for one on one discussions between investors and companies were also available.

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